Here, we presented why the results of simulation are slightly different between simulation by scenario and individual simulation.

In brief,

1) Limit of maximum infusion rate

    PION pump in individual infusion and simulation: 1200 ml/h, Pilot anesthesia or 2 pump: 1500 ml/h

    Simulation by scenario: set to infinity (very high speed was assumed)

2) Delta t

    Individual infusion and simulation: 2-30 s (adjustable)

    Simulation by scenario: 1 s (fixed)

3) Precision of calculation

    Individual infusion and simulation: based primarily on "INTEGER" for efficiency

    Simulation by scenario: based primarily on "DOUBLE"

4) Rounding issues in Excel program

    Individual infusion and simulation: stored in CSV file.

    Simulation by scenario: stored in XLS (excel) file.