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In the field of anesthesiology, target-controlled infusion (TCI) of hypnotics and opioids has been used for surgical patients.
TCI is sometimes called computer-controlled drug delivery.
This technology is based on the results of PKPD modeling. In clinical practice, medical doctors have administered drugs according to the conditions of their patients. Population analysis is a good tool to do so.
Here is a systematic review of TCI in Korean language.